Compile Data Set for Download or QSAR
Found 892 of ic50 data for polymerid = 50006042
LigandPNGBDBM50564984(CHEMBL4781373)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0495PPubMed
LigandPNGBDBM50568933(CHEMBL4847211)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568927(CHEMBL4853179)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50516677(CHEMBL4514780)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells assessed as reduction in MDP-induced IL8 production measured after 22 hrs by HTRF fluorescence ass...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8XKFPubMed
LigandPNGBDBM50568929(CHEMBL4870434)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568934(CHEMBL4864576)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568932(CHEMBL4858463)copy SMILES
Affinity DataIC50: 9nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568931(CHEMBL4859716)copy SMILES
Affinity DataIC50: 13nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50516677(CHEMBL4514780)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of NOD2 in human monocytes assessed as reduction in MDP-induced TNFalpha production preincubated for 30 mins followed by MDP-stimulation a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8XKFPubMed
LigandPNGBDBM4067(2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-meth...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM4077(2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-ethy...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50564997(CHEMBL4799077)copy SMILES
Affinity DataIC50: 16nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0495PPubMed
LigandPNGBDBM50568937(CHEMBL4861488)copy SMILES
Affinity DataIC50: 20nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568936(CHEMBL4864600)copy SMILES
Affinity DataIC50: 22nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50564987(CHEMBL4789724)copy SMILES
Affinity DataIC50: 26nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0495PPubMed
LigandPNGBDBM62288(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-[4-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
LigandPNGBDBM62288(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-[4-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
LigandPNGBDBM54356(2-bromobenzoic acid [2-[2,5-dimethyl-1-(2-oxolanyl...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0R8TPCBioAssay
LigandPNGBDBM3096(2-aminopyrido[2,3-d]pyrimidin-7(8H)-one deriv. | 6...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50564988(CHEMBL4793153)copy SMILES
Affinity DataIC50: 46nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0495PPubMed
LigandPNGBDBM50564979(CHEMBL4795976)copy SMILES
Affinity DataIC50: 46nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0495PPubMed
LigandPNGBDBM50564978(CHEMBL4776631)copy SMILES
Affinity DataIC50: 53nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0495PPubMed
LigandPNGBDBM50568942(CHEMBL4874031)copy SMILES
Affinity DataIC50: 94nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM54367(2-[(4E)-1-(1,3-benzothiazol-2-yl)-4-[1-(4-methoxya...)copy SMILEScopy InChI
Affinity DataIC50: 103nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0R8TPCBioAssay
LigandPNGBDBM50564977(CHEMBL4781705)copy SMILES
Affinity DataIC50: 121nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0495PPubMed
LigandPNGBDBM50564986(CHEMBL4788375)copy SMILES
Affinity DataIC50: 129nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0495PPubMed
LigandPNGBDBM50568935(CHEMBL4868894)copy SMILES
Affinity DataIC50: 136nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50568939(CHEMBL4849134)copy SMILES
Affinity DataIC50: 160nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM62251(MLS-0412140.0001 | cid_44182145 | cyclopropyl-[2-m...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
LigandPNGBDBM62251(MLS-0412140.0001 | cid_44182145 | cyclopropyl-[2-m...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
LigandPNGBDBM50568947(CHEMBL4867716)copy SMILES
Affinity DataIC50: 218nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM46401(1-(2-nitrophenyl)-3-[[(E)-(6-oxidanylidene-4-propo...)copy SMILEScopy InChI
Affinity DataIC50: 233nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0R8TPCBioAssay
LigandPNGBDBM50564976(CHEMBL4800115)copy SMILES
Affinity DataIC50: 243nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0495PPubMed
LigandPNGBDBM62261(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-met...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
LigandPNGBDBM62261(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-met...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
LigandPNGBDBM50568930(CHEMBL4871544)copy SMILES
Affinity DataIC50: 270nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50564980(CHEMBL4792496)copy SMILES
Affinity DataIC50: 323nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0495PPubMed
LigandPNGBDBM50564993(CHEMBL4782505)copy SMILES
Affinity DataIC50: 352nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0495PPubMed
LigandPNGBDBM50564975(CHEMBL4784430)copy SMILES
Affinity DataIC50: 390nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0495PPubMed
LigandPNGBDBM62257(MLS-0360553.0001 | cid_20901691 | cyclopropyl-[5-[...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
LigandPNGBDBM62257(MLS-0360553.0001 | cid_20901691 | cyclopropyl-[5-[...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
LigandPNGBDBM54409(4-[4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of NOD2 (unknown origin) expressed in HEK293T cells coexpressing NF-kappaB driven luciferase reporter gene by HTS primary assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6N0KPubMed
LigandPNGBDBM54409(4-[4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
LigandPNGBDBM50564981(CHEMBL4786742)copy SMILES
Affinity DataIC50: 420nMAssay Description:Inhibition of human NOD2 expressed in HEK293 cells coexpressing NFkappaB-SEAP reporter measured after 7 to 9 hrs by HEKBIue reporter assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0495PPubMed
LigandPNGBDBM50239686(CHEMBL4097753)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Antagonist activity at human NOD2 expressed in HEK-Blue cells assessed as inhibition of MDP-stimulated cell activation preincubated for 3 hrs followe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N839SPubMed
LigandPNGBDBM54195(2-[[2,5-dimethyl-1-(4-methylphenyl)-3-pyrrolyl]met...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23R0R8TPCBioAssay
LigandPNGBDBM50565443(CHEMBL4792557)copy SMILES
Affinity DataIC50: 480nMAssay Description:Antagonist activity at human NOD2 in HEK-Blue hNOD2 cells assessed as secreted alkaline phosphatase reporter activity preincubated for 3 hrs followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9MZ7PubMed
LigandPNGBDBM50568949(CHEMBL4875011)copy SMILES
Affinity DataIC50: 480nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
LigandPNGBDBM50556246(CHEMBL4740438)copy SMILES
Affinity DataIC50: 500nMAssay Description:Antagonist activity at NOD2 in HEK-Blue hNOD2 cells assessed as inhibition of MDP-induced NFkappaB activation-mediated SEAP release preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50F4PubMed
LigandPNGBDBM50568941(CHEMBL4852513)copy SMILES
Affinity DataIC50: 510nMAssay Description:Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP reporter assessed as reduction in L18-MDP-induced NF-kappaB activatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4863PubMed
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